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“It has exceeded expectations and I'm optimistic that this could change the way we treat hemophilia.”This is the first gene therapy trial to be conducted at the Medical Center, Summers says.He compares the trial's success so far to other UMMC firsts, such as heart and lung transplants and HIV treatment for the Mississippi Baby.“Since the early days of UMMC, our research efforts have been noted for innovative firsts,” Summers said.They used a FIX gene with a unique property.“This variant has five to ten times more activity than the wild-type [normal] FIX,” Sullivan said.“This means patients can receive a smaller dose of vector, which decreases the likelihood of an immune response.”To date, no trial participants have had an immune response.In Hallock's case, it also caused recurrent bleeding in his knees and ankles.

If you find any of the information in Psychology Today directory to be inaccurate in any way, please tell us by emailing: [email protected] assume full responsibility for the communications with any therapist you contact through Psychology Today directory.The results are promising.“The patients have experienced no bleeds, no immune response to the treatment and an improved quality of life,” said Dr.Spencer Sullivan, an assistant professor of pediatrics and hematologist who treated Hallock.Spark Therapeutics, a biotech company in Philadelphia, Pa.that specializes in gene therapy, developed the vector.

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